题目：tBuOK-Induced, NH₃·MeOH-Promoted Electrochemical C(sp³)−H Amination of Saturated Heterocycles with Sulfoximines

作者：Zi-Ru Xu (徐紫茹), Qing-Ru Zhu, Peng-Zhan Zhang, Hui Gao,*(高慧) and Pei-Long Wang* (王培龙)

单位：Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education; Anhui Provincial Key Laboratory of Synthetic Chemistry and Applications; School of Chemistry and Chemical Engineering, Huaibei Normal University, Huaibei, Anhui 235000, China

摘要：The t-BuOK-induced electrochemical C(sp³)−H amination of saturated heterocycles with sulfoximines was reported. t-BuOK rather than dangerous peroxides was used as the precursor of the tert-butoxy radical, which was induced by electrochemistry; this process has not been previously reported. Notably, we found that NH₃·MeOH can serve as a promoter in electrochemical oxidation reactions. This C−H/N−H cross-dehydrogenation coupling reaction produces only the green byproduct H₂ and has the advantages of atom economy, lack of transition metals, lack of external oxidants, and mild reaction conditions.

分区情况：SCI一区Top期刊

年、卷、页：2025, 27, 7785-7791

链接：//pubs.acs.org/doi/10.1021/acs.orglett.5c02042?ref=pdf