题目：C(sp³)–S Bond Formation via the Synergy of Oxidative With Reductive Photocatalysts Through Photoredox and Dual Hydrogen Atom Transfer Processes

   作者：Chao Zhou,^a (周超) Qianli Liang,^a Xinyi Zhu,^a Xue Zhang,^a Limei Liu,^a Yicheng Zhang,*^,a Jie Liu,^a Xiaoyu Xie,*^,a and Lei Wang*^,a,b,c

       单位：^a College of Chemistry and Materials Science, Key Laboratory of Green and Precise Synthetic Chemistry, Ministry of Education, Huaibei Normal University, Huaibei, Anhui   235000, P. R. China.

         ^bAdvanced Research Institute and School of Pharmaceutical Sciences, Taizhou University, Taizhou, Zhejiang 318000, P. R. China.

        ^cCollege of Material Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou,  Zhejiang, 311121, P. R. China.

       摘要：A primary objective of organic synthesis is to establish a catalytic methodology that is mild, straightforward, and economically efficient. Thioesters are widely employed in the realms of physiology, pharmacology, and agriculture. It is imperative to continuously expand the range of sulfur-containing precursors to keep pace with the cutting-edge        advancements in the field of organic sulfur chemistry. Our research has uncovered that polysulfide anions (K₂S_x), which serve as reducing catalysts, can also effectively act as sulfur    reagents, providing the formation of C(sp³)–S bonds through a photoredox catalysis with an oxidative photocatalyst tetrabutylammonium decatungstate (TBADT) and dual hydrogen atom  transfer (DHAT) process. In a pioneering study, we present a combinatorial strategy of an oxidative photocatalyst TBADT with a reductive photocatalyst K₂S_x, enabled a photo-induced  three-component coupling reaction of simple aldehydes with alkanes containing C(sp³)–H and polysulfide anions. A numbers of thioester derivatives were successfully obtained in good yields, while a by-product H₂S was captured and identified by gas chromatography analysis. Concurrently, density functional theory (DFT) calculations provided the theoretical support of reaction mechanism.

影响因子：14.1

分区情况：一区

链接：//doi.org/10.1002/advs.202415936

年、卷、页：2025, e15936.

（文、图：周超 / 审核：韩满意 / 审校：曹静 / 终审：杨振兴）